EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types

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EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types.

BACKGROUND Immediate early genes (IEGs) encode transcription factors which serve as first line response modules to altered conditions and mediate appropriate cell responses. The immediate early response gene EGR1 is involved in physiological adaptation of numerous different cell types. We have previously shown a role for EGR1 in controlling processes supporting chondrogenic differentiation. We ...

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ژورنال

عنوان ژورنال: BMC Musculoskeletal Disorders

سال: 2016

ISSN: 1471-2474

DOI: 10.1186/s12891-016-0979-x